The brand new MWHS research was designed to test the fresh hypothesis one obesity is actually with the sizzling hot flashes due to: a) very early ovarian hair follicle losses/incapacity, b) chosen hereditary polymorphisms about family genes one to encode minerals you to synthesize and you can wear-out sex steroid drugs and you may/and/or receptors that enable architecture to resolve sex steroid drugs, or c) mechanisms involving very early follicle losses/incapacity, altered sex steroid hormone levels, and hereditary polymorphisms within the family genes you to encode minerals one synthesize and you will degrade sex steroids and you can/otherwise receptors one to respond to sex steroid drugs (so it the main study are but really is presented)

Specific analyses which have been completed to time about MWHS include: 1) identification away from chance issues for the stretched duration of sizzling hot flashes plus the time of height sizzling hot flashes severity ; 2) study of the fresh relationships between market qualities, wellness routines, hormones levels, therefore the connection with one, latest, more severe, and more constant midlife sizzling hot flashes ; 3) examination of the fresh relationship between quitting smoking and you can midlife sizzling hot flashes ; 4) study of brand new associations between Body mass index, Bmi transform, and you can pounds alter and you may midlife sizzling hot flashes ; 5) study of if or not high urinary degrees of phthalate metabolites are associated having an elevated risk of midlife scorching flashes ; 6) examination of new relationships ranging from Bmi, tobacco, alcoholic drinks intake, and you can hormones density with ovarian volume among midlife women ; and you can seven) identification out-of activities in the sexual hobby during the menopausal transition . Continuarea →