Several inhabitants-established degree and observational studies have shown that oophorectomy is relevant having a greater chance of colorectal cancers (CRC), and you will hormones replacement therapy has been regarding the a reduction in the risk of colorectal malignant tumors. This study was accomplished to research if or not hysterectomy, which may change the levels of female hormones, are regarding the a threat of cancer of the certain gastrointestinal region.

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This population-established retrospective cohort analysis was conducted having fun with insurance research provided with the Insurance Review and you will Review Services (HIRA) of . The fresh new hysterectomy class integrated 40- to 59-year-old women that undergone hysterectomy having uterine leiomyoma otherwise uterine endometriosis out-of . This new manage class incorporated women old forty to help you 59 age whom visited medical establishments to own medical test regarding .

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The new hysterectomy and you can low-hysterectomhy teams made up 66,204 and you will 89,768 victims, respectively. The fresh new median years on low-hysterectomy group and you can hysterectomy classification have been 48 (range: 43–53) and you will 46 (range: 44–49) age, respectively. On the unadjusted outcome of the research, all colorectal cancer (CRC) improved regarding the hysterectomy alone classification (Hours step one.222, 95% trust period (CI) 1.0step one6–step one.47, p = 0.033), sigmoid a cancerous colon improved about hysterectomy alone classification (Hour step 1.71, 95% CI step 1.073–dos.724, p = 0.024), and you may rectal cancers increased on hysterectomy that have adnexal businesses category (Time 1.924, 95% CI 1.073–dos.724, p = 0.002). Continuarea →